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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AHR All Species: 18.48
Human Site: S450 Identified Species: 33.89
UniProt: P35869 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35869 NP_001612.1 848 96147 S450 T S T L S K D S L N P S S L L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103903 877 98936 S477 K S T L N K D S L N P S S L L
Dog Lupus familis XP_532485 853 96719 S449 K S T L N K D S L N P N S L L
Cat Felis silvestris
Mouse Mus musculus P30561 848 94998 S444 Q S T P S K D S F H P S S L M
Rat Rattus norvegicus P41738 853 96208 S448 Q S T P S K D S F H P N S L M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514645 843 94282 P493 Y E V T F P F P A L M D P L Q
Chicken Gallus gallus NP_989449 858 96204 P449 L H G D S V D P N S L L G A M
Frog Xenopus laevis NP_001082693 834 93568 S439 N E P P V K P S S L L G A M M
Zebra Danio Brachydanio rerio NP_001019987 940 104828 D447 K S S K D D L D P S S L L G A
Tiger Blowfish Takifugu rubipres NP_001033051 973 106418 P445 L A K D G L D P G S L L G A L
Fruit Fly Dros. melanogaster P05709 697 76457 G351 R F L T K G G G W V W V Q S Y
Honey Bee Apis mellifera XP_394737 1180 127698 S718 A A V A A A Y S N L N T M Y P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780848 1375 154368 D470 P P G V S M G D M P P G M G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 90 85.1 N.A. 72.1 72.4 N.A. 61.7 65.3 56.5 43.1 41.7 20.1 21.5 N.A. 25.8
Protein Similarity: 100 N.A. 93.5 91.2 N.A. 83.1 83.9 N.A. 71.6 76.5 70.7 57.8 56.1 37.7 36.8 N.A. 39.5
P-Site Identity: 100 N.A. 86.6 80 N.A. 66.6 60 N.A. 6.6 13.3 13.3 6.6 13.3 0 6.6 N.A. 13.3
P-Site Similarity: 100 N.A. 93.3 93.3 N.A. 80 80 N.A. 6.6 26.6 33.3 20 26.6 0 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 0 8 8 8 0 0 8 0 0 0 8 16 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 16 8 8 54 16 0 0 0 8 0 0 0 % D
% Glu: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 8 0 8 0 16 0 0 0 0 0 0 % F
% Gly: 0 0 16 0 8 8 16 8 8 0 0 16 16 16 8 % G
% His: 0 8 0 0 0 0 0 0 0 16 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 24 0 8 8 8 47 0 0 0 0 0 0 0 0 0 % K
% Leu: 16 0 8 24 0 8 8 0 24 24 24 24 8 47 31 % L
% Met: 0 0 0 0 0 8 0 0 8 0 8 0 16 8 31 % M
% Asn: 8 0 0 0 16 0 0 0 16 24 8 16 0 0 0 % N
% Pro: 8 8 8 24 0 8 8 24 8 8 47 0 8 0 8 % P
% Gln: 16 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 47 8 0 39 0 0 54 8 24 8 24 39 8 0 % S
% Thr: 8 0 39 16 0 0 0 0 0 0 0 8 0 0 0 % T
% Val: 0 0 16 8 8 8 0 0 0 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 8 0 0 0 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _